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綠色新化學(xué)品研發(fā)，需要早期毒性鑒定，預(yù)防發(fā)生風(fēng)險(xiǎn)?，F(xiàn)有化學(xué)品評(píng)估要求快速進(jìn)行毒性預(yù)測(cè)，以減少動(dòng)物的使用，使用新技術(shù)提高評(píng)價(jià)的準(zhǔn)確性，克服傳統(tǒng)方法周期長(zhǎng)和外推的不確定性。機(jī)構(gòu)基于計(jì)算機(jī)輔助篩選、體外細(xì)胞篩選及體內(nèi)動(dòng)物篩選實(shí)驗(yàn)體系，建立分級(jí)篩選策略，對(duì)化合物和生物小分子的理化性質(zhì)、ADME性質(zhì)、毒理學(xué)和環(huán)境效應(yīng)進(jìn)行預(yù)測(cè)和篩選。通過(guò)CMR\EDC\PBT等危害終點(diǎn)預(yù)測(cè)，能夠?qū)ξ镔|(zhì)毒性快速分級(jí)。結(jié)合計(jì)算模型暴露風(fēng)險(xiǎn)評(píng)估，為建立高危優(yōu)先管理物質(zhì)服務(wù)。[View More+]

Physio-chemical Property

This laboratory can supply physical-chemical test service for domestic and foreign customers in their pesticide and chemicals registration. The registration countries and regions involved are European Union, United States, Canada, Brazil, Argentina, Mexico, Ukraine, Peru, Uruguay, Chile, Colombia and other countries. At present, the laboratory can do 56 kinds of physical-chemical tests, which can meet the requirements of international and domestic chemicals and pesticide product registration. This laboratory is one of the few testing institutions in China that can do both explosive properties (shock, friction and kenan) and saturated vapor pressure (Isothermal Thermogravimetry) .[View More+]

Health Effects

As one of the earliest safety evaluation institutions in China, we have more than 50 years of experience in toxicology studies, and have gradually developed from a toxicology group into a large safety evaluation center with multiple GLP certifications from domestic and abroad. According to registration requirements, a complete set of health toxicology studies including acute toxicity, repeated dose toxicity, genotoxicity, reproductive toxicity and carcinogenicity can be conducted in consistent with OECD GLP to provide comprehensive data and reports for various new chemicals. [View More+]

Effects on Biotic Systems

The laboratory has well-equipped facilities, complete instruments and comprehensive personnel capacity. A complete set of tests for the declaration of new chemicals to the Ministry of Environmental Protection from the first to the fourth levels can be carried out in this laboratory. And tests compliance with OECD GLP can be carried out according to the OECD test guidelines to provide customers with environmental safety test data for domestic and foreign registration. In addition to common environmental safety tests, services also includes high-tier tests such as pesticide aquatic ecosystem (mesocosm) test, species sensitivity distributions test, field dissipation, field monitoring tests, occupational exposure assessment. The department also undertakes environmental risk assessment business. The GLP ecological test and environmental risk assessment of ballast water can also be carried out. At the mean while, service of rapid toxicity screening test for compounds can also be provided.[View More+]

Environmental Fate and Behaviour

The Environmental Toxicology Department of Safety Assessment Center was founded in 1998, and began to conduct environmental behavior test and environmental ecotoxicology of chemicals in 2004. The Environmental Toxicology Department is one of the first GLP qualified laboratories of the Ministry of Environmental Protection. In 2014, it achieved OECD GLP qualification from the Netherlands in the field of environmental behavior and environmental ecology. And it has successfully passed two reviews in 2016 and 2018.[View More+]

Risk Assessment and Regulatory Advisory

The company is committed to providing policy consultation, registration and testing, risk assessment and file preparation services for new chemical production/import enterprises and overseas enterprises exporting to China.[View More+]